Beta Catenin and Depression

Peter Forster Basic Science, Major Depression, Psychobiology

Beta catenin is a molecule that may play a key role in preventing depression in those exposed to stress, at least if mice and humans share the same biology. Beta catenin is involved in a number of quite different functions in the cell. To give you an idea, it may be involved in the development of cancer (it is a …

Exercise and Stress – How Exercise Prevents Depression

Peter Forster Major Depression, Physical Conditions and Health, Treatments of Depression

Exercise seems to reduce stress. But how does this work? And what about exercise effects on depression? An article in the New York Times summarizes¬†a recent publication¬†in the journal Cell which may explain how exercise prevents depression. A wealth of research shows that regular exercise reduces the risk of depression. A very large study in Britain, for example, suggested that …

Cortisol and Depression

Peter Forster Psychobiology

A middle aged man with depression came in today for his first psychiatric evaluation. He had lots of questions about the relationship between cortisol and depression, because his first serious depression, at age 45, occurred in the context of a severe work stress. And this work stress was associated with many physical manifestations of stress – fatigue, severely disrupted sleep, …